BREADR - Estimating genetic relatedness for extremely low-coverage DNA samples
BREADR was developed to estimate genetic relatedness up to the second-degree for samples with very few overlapping sites. We wrote BREADR as an easy-to-use and install R package, available on CRAN.
ChASM (Chromosomal Aneuploidy Screening Methodology) is a statistically rigorous Bayesian approach for screening data sets for automsomal and sex chromosomal aneuploidies.
Genetic and cultural transformations in the prehistory of Transylvania
The genetic prehistory of Neolithic to Late Bronze Age Transylvania is under-sampled, and poorly understood. Here we aim to explore the genetic landscape of Transylvania, while comparing to nearby regions, over the Late Neolithic to the Late Bronze Age.
One- and two-sample Tests for Distributions of Runs of Homozygosity
Long runs of homozygosity (ROH) are inherited long without variation, often due to parental relatedness. Hypothesis tests considering: the proportion on non-zero ROH carriers, and the overall mean ROH are derived. One- and two-sample tests are derived.